Yes. They are being used in China. The problem with just calling them the drugs of choice is that the data is a mess and wasn't taken consistently or in a controlled manner. It was a free for fall, so the study needs to be completed in a more orderly fashion. The drugs are already widely in use and approved for other disease, so putting them into trial is much quicker than it otherwise would be. All if the drugs mentioned are antiretroviral HIV immunosuppressants or Antimalarials. The thing that ends up killing many people with Covid 19 is the cytokine storm that is created by your own body in fighting the disease. Stopping or slowing cytokines stops you from dying, apparently.
I had read about the drugs a number of weeks ago when clinical trials for them started being announced in a a few countries, including China.
Basically, scientists [worldwide] had gone through about 40,000 existing drugs looking for ones that showed liklihood of having effects on covid based on in vivo and in vitro studies done previously, including studies done wrt SARS and MERS.
The two the Austrialians are discussing, one an HIV antiviral and the other Chloroquine/Hydroxychloroquine were two of the most promising that came out of culling down the 40,000. I paid the most attention to the Chloroquine/Hydroxychloroquine as I currently take Hydroxychloroquine for RA. Basically in vitro (ie in the lab) studies it has very promising results. This is a good explanation for it:
https://watermark.silverchair.com/c...nlOpPBAc5hwS1Chdb0xQmEadbWQVtQjmgw8a6fXJxR0UQ
Now they have to do the clinical trials to see if it ACTUALLY works in humans, which are underway in China and a number of other countries.
Both of the antivirals work at messing with the activity of the virus itself, impacting its ability to infect/reproduce/etc.
There are other studies looking at ways to modulate the cytokine storm that is the cause of death in some cases. One of the drugs under study for that is actually an antibiotic [not because the antibiotic is killing anything in the case of covid, but because the drug apparently has an effect on the immune system which can modulate it and reduce the cytokine storm in some cases].
As an aside, some countries are now taking action to prevent export and hording of these drugs.
Hopefully they will get some effective treatments. Whether that will have an impact on how long all of this lasts, I don't know.
We have a cruise booked for NEXT summer 2021. We are hoping it can still go forward, but even if cruises are back on by then we will still have to do some serious thinking on whether we tackle a cruise at that point or wait another year into 2022. Part of that decision will hinge on if there is an effective vaccine or not, etc. We are at higher risk for complications, and that is also a factor in decision-making.
SW