they have had a great run with both the Marvel Universe movies (those Disney ones that all tie together) and the "orphans" as in Spiderman and the X-men movies which are other studios...of course, they haven't all been hits, lets not forget Judge Dredd, The Punisher, Ghost Rider, Electra, Daredevil, The Fantastic Four, both versions of The Hulk...granted most the misses were pre-Disney getting involved.
I really doubt DC is going to be able to match with Batman vs. Superman and the Justice League series, maybe had they done so after Batman Begins, but the Man of Steel wasn't all that great.